Article
Transcomplementation between different types of respiration-deficient mitochondria with different pathogenic mutant mitochondrial DNAs.
The Journal of biological chemistry - 16 Apr 1999
Takai D, Isobe K, Hayashi J
Abstract excerpt
Two cell lines were used for determination of whether interaction occurred between different types of respiration-deficient mitochondria. One was a respiration-deficient rho- cell line having mutant mitochondrial DNA (mtDNA) with a 5,196-base pair deletion including five tRNA genes (tRNAGly, Arg, Ser(AGY), Leu(CUN), His), DeltamtDNA5196, causing Kearns-Sayre syndrome. The other was a respiration-deficient syn-...
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