Isolation, characterization and epistasis of fluoride-resistant mutants of Caenorhabditis elegans.

doi:10.1093/genetics/136.1.145

Back to search

Article

Isolation, characterization and epistasis of fluoride-resistant mutants of Caenorhabditis elegans.

Genetics - 1 Jan 1994

Katsura I, Kondo K, Amano T, Ishihara T, Kawakami M

Abstract excerpt

We have isolated 13 fluoride-resistant mutants of the nematode Caenorhabditis elegans. All the mutations are recessive and mapped to five genes. Mutants in three of the genes (class 1 genes: flr-1 X, flr-3 IV, and flr-4 X) are resistant to 400 micrograms/ml NaF. Furthermore, they grow twice as sl...

Topics

Animals
Caenorhabditis elegans
Chromosome Mapping
Crosses, Genetic
DNA Damage
Drug Resistance
Female
Genes, Recessive
Genetic Markers
Heterozygote
Male
Phenotype
Reproduction
Sodium Fluoride

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.