Article
Expression of PACT is regulated by Sp1 transcription factor.
Gene - 15 Feb 2007
Fasciano Stephen, Kaufman Amanda, Patel Rekha C
Abstract excerpt
PACT is a stress-modulated, cellular activator of interferon (IFN)-induced double-stranded (ds) RNA-activated protein kinase (PKR) and is an important regulator of PKR-dependent signaling pathways. The research presented here is aimed at understanding the regulation of PACT expression in mammalian cells. PACT is expressed ubiquitously in different cell types at varying abundance. We have characterized the...
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