Hypercapnic ventilatory responses in mice differentially susceptible to acute ozone exposure.

doi:10.1152/jappl.1993.75.6.2613

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Article

Hypercapnic ventilatory responses in mice differentially susceptible to acute ozone exposure.

Journal of applied physiology (Bethesda, Md. : 1985) - 1 Dec 1993

Tankersley C G, Fitzgerald R S, Mitzner W A, Kleeberger S R

Abstract excerpt

Susceptibility to ozone (O3)-induced pulmonary inflammation is greater in C57BL/6J (B6) than in C3H/HeJ (C3) strain of mice. We tested the hypothesis that altered ventilatory control occurs in B6 mice to a greater extent than in C3 mice after acute O3 exposure. Age-, sex-, and weight-matched C3 a...

Topics

Animals
Hypercapnia
Male
Mice
Mice, Inbred C3H
Mice, Inbred C57BL
Ozone
Phenotype
Plethysmography, Whole Body
Respiratory Mechanics
Species Specificity
Tidal Volume

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