Article
A genetic model for evaluation of susceptibility to ozone-induced inflammation.
The American journal of physiology - 1 Jun 1990
Kleeberger S R, Bassett D J, Jakab G J, Levitt R C
Abstract excerpt
We examined ozone-induced airway inflammatory responses in inbred mice, and progeny of crosses between them, to investigate genetic susceptibility to ozone. Nine strains of male mice (18-23 g, 5-7 wk) were exposed for 3 h to 2 ppm ozone (O3) or filtered air (control), and pulmonary inflammation w...
Topics
- Animals
- Crosses, Genetic
- Endothelium
- Female
- Genetic Predisposition to Disease
- Inflammation
- Lung
- Lymphocytes
- Macrophages
- Male
- Mice
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Mice, Inbred Strains
- Neutrophils
- Ozone
- Species Specificity