Article
Genetic determinants of acute hypoxic ventilation: patterns of inheritance in mice.
Journal of applied physiology (Bethesda, Md. : 1985) - 1 Jun 2000
Tankersley C G, Elston R C, Schnell A H
Abstract excerpt
Acutely lowering ambient O(2) tension increases ventilation in many mammalian species, including humans and mice. Inheritance patterns among kinships and between mouse strains suggest that a robust genetic influence determines individual hypoxic ventilatory responses (HVR). Here, we tested specific genetic hypotheses to describe the inheritance patterns of HVR phenotypes among two inbred mouse strains and their...
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