Article
Effects of Ozone on Sickness and Depressive-like Behavioral and Biochemical Phenotypes and Their Regulation by Serum Amyloid A in Mice.
International journal of molecular sciences - 13 Jan 2023
Baumann Kristen K, Liang W Sandy, Quaranta Daniel V, Wilson Miranda L, Asrat Helina S, Thysell Jarl A, Sarchi Angelo V, Banks William A, Erickson Michelle A
Abstract excerpt
Ozone (O3) is an air pollutant that primarily damages the lungs, but growing evidence supports the idea that O3 also harms the brain; acute exposure to O3 has been linked to central nervous system (CNS) symptoms such as depressed mood and sickness behaviors. However, the mechanisms by which O3 inhalation causes neurobehavioral changes are limited. One hypothesis is that factors in the circulation bridge...
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