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Article

Prevalence of beta allele of the insulin gene in type II diabetes mellitus.

Human genetics - 1 Mar 1994

Horst-Sikorska W, Zoll B, Kwiatkowska J, Willms B, Kraszewski A, Horst A, Slomski R

Abstract excerpt

Fifty-two patients and 36 controls were compared in a search for insulin gene variants among type II diabetic patients with fasting hyperinsulinemia (above 90 microU/ml) and a fasting C-peptide to insulin molar ratio between 1.11 and 1.50. Alpha and beta alleles of the insulin gene were characterized by restriction analysis of polymerase chain reaction (PCR) products and direct sequencing. The more frequent...

Topics

Adult
Aged
Aged, 80 and over
Alleles
Base Sequence
C-Peptide
DNA
Deoxyribonucleases, Type II Site-Specific
Diabetes Mellitus, Type 2
Female
Gene Frequency
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Insulin

Male

Middle Aged

Molecular Sequence Data

Polymerase Chain Reaction

Source

Identifiers

PMID: 8125485
DOI: 10.1007/BF00212031

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8125485-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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