Article
Insulin receptor gene mutations in iranian patients with type II diabetes mellitus.
Iranian biomedical journal - 1 Jul 2009
Kazemi Bahram, Seyed Negar, Moslemi Elham, Bandehpour Mojgan, Bikhof Torbati Maryam, Saadat Navid, Eidi Akram, Ghayoor Elham, Azizi Fereydoun
Abstract excerpt
BACKGROUND: Patients with diabetes mellitus type II suffer from hyperglycemia because they are not able to use the insulin that they produce, often due to inadequate function of insulin receptors. There are some evidences that this deficiency is inherited in a dominant autosomal manner and leads to the malfunction of the pancreatic beta cells resulting in insulin excretion disorders. In this study, we sought to...
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