Article
Restriction fragment length polymorphism of the insulin receptor gene, type 2 diabetes and insulin binding.
Diabete & metabolisme - 1 Jan 2000
Menzel S, Neumer C, Zorad S, Klimes I, Langerova H, Svabova E, Macho L, Zühlke H
Abstract excerpt
In searching for a genetic marker of type 2 diabetes we estimated the frequency of alleles of the Bgl II restriction fragment length polymorphism (RFLP) of the insulin receptor gene in a group of type II diabetic patients (n = 50), characterized by OGTT (glucose, insulin, C-peptide) and insulin r...
Topics
- Bacterial Proteins
- C-Peptide
- DNA Probes
- Deoxyribonucleases, Type II Site-Specific
- Diabetes Mellitus, Type 2
- Erythrocytes
- Female
- Genetic Carrier Screening
- Genetic Markers
- Genotype
- Homozygote
- Humans
