Article
Screening for insulin receptor gene DNA polymorphisms associated with glucose intolerance in a Scandinavian population.
Diabetologia - 1 Apr 1991
Sten-Linder M, Vilhelmsdotter S, Wedell A, Stern I, Pollare T, Arner P, Efendić S, Luft R, Luthman H
Abstract excerpt
The significance of insulin receptor gene variants in the aetiology of Type 2 (non-insulin-dependent) diabetes mellitus has been investigated by analysis of restriction fragment length polymorphisms in a genetically homogeneous Swedish population. Seven polymorphisms were analysed, spanning functionally important regions of the insulin receptor locus. Four of these polymorphisms were mapped more accurately within...
Topics
- Blood Glucose
- Body Mass Index
- DNA
- DNA Restriction Enzymes
- Diabetes Mellitus, Type 2
- Female
- Genotype
- Glucose Tolerance Test
- Humans
- Insulin
- Leukocytes
