Article
Regulation of progression through the G1 phase of the cell cycle by the rum1+ gene.
Nature - 20 Jan 1994
Moreno S, Nurse P
Abstract excerpt
The rum1+ gene is identified as a new regulator of G1 progression in fission yeast. It influences three aspects of G1 regulation: determination of the length of G1, dependence of S phase upon completion of mitosis, and restraint of mitosis until G1 is finished. We propose that it has a central role in regulating the G1 phase of the cell cycle.
Topics
- Amino Acid Sequence
- Base Sequence
- CDC2 Protein Kinase
- Cell Cycle
- Cyclin B
- Cyclins
- DNA Replication
- DNA, Fungal
- Fungal Proteins
- G1 Phase
- Genes, Fungal
- Models, Genetic
- Molecular Sequence Data