Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulated mRNA stability of the Cdk inhibitor Rum1 links nutrient status to cell cycle progression.

Current biology : CB - 2 Dec 2003

Daga Rafael R, Bolaños Pilar, Moreno Sergio

Abstract excerpt

BACKGROUND: The survival of a cell depends on continuous sensing of the nutritional environment and appropriate coordination of the cell cycle. The fission yeast Schizosaccharomyces pombe is an excellent model system in which to study these processes. In the presence of nutrients, fission yeast cells grow and divide, spending most of their time in G2; when nutrients are limiting, they are promoted into mitosis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Northern
Share to Cell Cycle
Share to G1 Phase

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Fungal

Share to Nitrogen

Share to RNA Stability

Share to Schizosaccharomyces

Share to Schizosaccharomyces pombe Proteins

Source

Identifiers

PMID: 14653990
DOI: 10.1016/j.cub.2003.10.061

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulated mRNA stability of the Cdk inhibitor Rum1 links nutrient status to cell cycle progression.PMID 14653990Read ↗

Regulation of progression through the G1 phase of the cell cycle by the rum1+ gene.Semantic proximity Read ↗

Liz1p, a novel fission yeast membrane protein, is required for normal cell division when ribonucleotide reductase is inhibited.Semantic proximity Read ↗

The puc1 cyclin regulates the G1 phase of the fission yeast cell cycle in response to cell size.Semantic proximity Read ↗

RNA-Binding Protein Rnc1 Regulates Cell Length at Division and Acute Stress Response in Fission Yeast through Negative Feedback Modulation of the Stress-Activated Mitogen-Activated Protein Kinase Pathway.Semantic proximity Read ↗

The Cdk inhibitors p25rum1 and p40SIC1 are functional homologues that play similar roles in the regulation of the cell cycle in fission and budding yeast.Semantic proximity Read ↗

Fission yeast Tor2 promotes cell growth and represses cell differentiation.Semantic proximity Read ↗

The Double Life of UPF1 in RNA and DNA Stability PathwaysSemantic proximity Read ↗

Initiation of the TORC1-regulated G0 program requires Igo1/2, which license specific mRNAs to evade degradation via the 5'-3' mRNA decay pathway.Semantic proximity Read ↗

p25rum1 orders S phase and mitosis by acting as an inhibitor of the p34cdc2 mitotic kinase.Semantic proximity Read ↗

ago1 and dcr1, two core components of the RNA interference pathway, functionally diverge from rdp1 in regulating cell cycle events in Schizosaccharomyces pombe.Semantic proximity Read ↗

Analysis of the Schizosaccharomyces pombe cyclin puc1: evidence for a role in cell cycle exit.Semantic proximity Read ↗

A WD repeat protein controls the cell cycle and differentiation by negatively regulating Cdc2/B-type cyclin complexes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.