Regulated mRNA stability of the Cdk inhibitor Rum1 links nutrient status to cell cycle progression.

doi:10.1016/j.cub.2003.10.061

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Article

Regulated mRNA stability of the Cdk inhibitor Rum1 links nutrient status to cell cycle progression.

Current biology : CB - 2 Dec 2003

Daga Rafael R, Bolaños Pilar, Moreno Sergio

Abstract excerpt

BACKGROUND: The survival of a cell depends on continuous sensing of the nutritional environment and appropriate coordination of the cell cycle. The fission yeast Schizosaccharomyces pombe is an excellent model system in which to study these processes. In the presence of nutrients, fission yeast cells grow and divide, spending most of their time in G2; when nutrients are limiting, they are promoted into mitosis...

Topics

Base Sequence
Blotting, Northern
Blotting, Western
Cell Cycle
Chromosome Mapping
Crosses, Genetic
G1 Phase
Gene Expression Regulation, Fungal
Molecular Sequence Data
Mutation
Nitrogen
RNA Stability
RNA, Messenger
Schizosaccharomyces
Schizosaccharomyces pombe Proteins
Sequence Analysis, DNA
Sequence Deletion

Source

Open in PubMed

Identifiers

PMID: 14653990
DOI: 10.1016/j.cub.2003.10.061

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