Article
Fine deletion mapping on the long arm of chromosome 9 in sporadic and familial basal cell carcinomas.
Human molecular genetics - 1 Jan 1995
Shanley S M, Dawkins H, Wainwright B J, Wicking C, Heenan P, Eldon M, Searle J, Chenevix-Trench G
Abstract excerpt
Basal cell carcinomas (BCCs) are the most common sporadic cancers worldwide. They are also a cardinal manifestation of a familial cancer predisposition syndrome, naevoid BCC syndrome (NBCCS). The gene responsible for NBCCS is likely to be a tumour suppressor gene and has been genetically mapped to a 2cM region between microsatellite markers, D9S196 and D9S180 at 9q22.3-q31. 101 BCCs (63 sporadic and 38 familial)...
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