Article
Fine deletion mapping on the long arm of chromosome 9 in sporadic and familial basal cell carcinomas.
Human molecular genetics - 1 Jan 1995
Shanley S M, Dawkins H, Wainwright B J, Wicking C, Heenan P, Eldon M, Searle J, Chenevix-Trench G
Abstract excerpt
Basal cell carcinomas (BCCs) are the most common sporadic cancers worldwide. They are also a cardinal manifestation of a familial cancer predisposition syndrome, naevoid BCC syndrome (NBCCS). The gene responsible for NBCCS is likely to be a tumour suppressor gene and has been genetically mapped t...
Topics
- Adult
- Chromosome Deletion
- Chromosome Mapping
- Chromosomes, Human, Pair 9
- Genetic Predisposition to Disease
- Heterozygote
- Humans
- Neoplasms, Basal Cell
- Nevus
- Skin Neoplasms
- Syndrome
