Article
Melanoma-derived interleukin 6 inhibits in vivo melanoma growth.
The Journal of investigative dermatology - 1 Mar 1994
Armstrong C A, Murray N, Kennedy M, Koppula S V, Tara D, Ansel J C
Abstract excerpt
Malignant melanomas are capable of producing a wide range of cytokines with multiple biologic functions, including interleukin 6 (IL-6). We have observed an inverse relationship between IL-6 production of three B16-derived murine melanoma cell lines (NP133, HFH18, and HFH(M)) and the tumorigenici...
Topics
- Animals
- Antibodies, Neoplasm
- Cell Transformation, Neoplastic
- Genetic Variation
- Immunohistochemistry
- Interleukin-6
- Melanoma
- Mice
- Mice, Nude
- Transfection
- Tumor Cells, Cultured
