Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of interleukin-8 in primary and metastatic malignant melanoma of the skin.

Melanoma research - 1 Aug 1999

Singh R K, Varney M L, Bucana C D, Johansson S L

Abstract excerpt

It was recently demonstrated that interleukin-8 (IL-8) is produced by cultured melanoma cells and acts as an essential autocrine growth factor. Earlier studies from our laboratory demonstrated a direct correlation between IL-8 expression in human variant cell lines and their metastatic potential in nude mice. In the present study we examined the expression of IL-8 in human malignant melanomas using...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Disease Progression
Share to Immunohistochemistry

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Interleukin-8

Share to Lymphatic Metastasis

Share to Melanoma

Share to Skin Neoplasms

Share to Soft Tissue Neoplasms

Source

Identifiers

PMID: 10504057
DOI: 10.1097/00008390-199908000-00007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of interleukin-8 in primary and metastatic malignant melanoma of the skin.PMID 10504057Read ↗

Multiple features of advanced melanoma recapitulated in tumorigenic variants of early stage (radial growth phase) human melanoma cell lines: evidence for a dominant phenotype.Semantic proximity Read ↗

Metastatic lesions with and without interleukin-18-dependent genes in advanced-stage melanoma patients.Semantic proximity Read ↗

Level of interleukin-8 expression by metastatic human melanoma cells directly correlates with constitutive NF-kappaB activity.Semantic proximity Read ↗

The prognostic significance and impact of the CXCR4-CXCR7-CXCL12 axis in primary cutaneous melanoma.Semantic proximity Read ↗

Metastatic potential of human melanoma cells in nude mice--characterisation of phenotype, cytokine secretion and tumour-associated antigens.Semantic proximity Read ↗

A potential role for interleukin-8 in the metastatic phenotype of breast carcinoma cells.Semantic proximity Read ↗

Melanoma-derived interleukin 6 inhibits in vivo melanoma growth.Semantic proximity Read ↗

Differential Expression of Vascular Endothelial Growth Factor–A Isoforms at Different Stages of Melanoma ProgressionSemantic proximity Read ↗

CXCL10 reduces melanoma proliferation and invasiveness in vitro and in vivoSemantic proximity Read ↗

Bcl‐2 overexpression in melanoma cells increases tumor progression‐associated properties and in vivo tumor growthSemantic proximity Read ↗

Gene Regulation in Melanoma Progression by the AP‐2 Transcription FactorSemantic proximity Read ↗

Prognostic significance of tumor iNOS and COX-2 in stage III malignant cutaneous melanoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.