Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of Cellular Processes by Interleukin‐16 in Homeostasis and Cancer

29 Jul 2013

Abstract excerpt

Interleukin-16 (IL-16) is generated as a precursor molecule that is cleaved by caspase-3 to produce a pro-IL-16 molecule that functions as a regulator of T cell growth, and a secreted peptide that functions as a CD4 and/or CD9 ligand for induction of cell motility and activation. IL-16 has been predominantly studied as a contributing factor in the orchestration of an immune response; however, more recently IL-16...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to Immune Cell Function and Interaction
Share to Whipple's Disease and Interleukins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23893766
DOI: 10.1002/jcp.24441

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of Cellular Processes by Interleukin‐16 in Homeostasis and CancerPMID 23893766Read ↗

lnterleukin-16: The Ins and Outs of Regulating T-Cell ActivationSemantic proximity Read ↗

Loss of nuclear pro-IL-16 facilitates cell cycle progression in human cutaneous T cell lymphoma.Semantic proximity Read ↗

HPV16-associated tumors control myeloid cell homeostasis in lymphoid organs, generating a suppressor environment for T cells.Semantic proximity Read ↗

Nuclear pro-IL-16 regulation of T cell proliferation: p27(KIP1)-dependent G0/G1 arrest mediated by inhibition of Skp2 transcription.Semantic proximity Read ↗

Insights into the Mechanisms of Action of MDA-7/IL-24: A Ubiquitous Cancer-Suppressing ProteinSemantic proximity Read ↗

Loss of p16: A Bouncer of the Immunological Surveillance?Semantic proximity Read ↗

Tumor-related interleukins: old validated targets for new anti-cancer drug developmentSemantic proximity Read ↗

The chemical biology of IL-12 production via the non-canonical NFkB pathwaySemantic proximity Read ↗

IL-6 involvement in epithelial cancers.Semantic proximity Read ↗

Th17 cells in cancer: help or hindrance?Semantic proximity Read ↗

Interleukin 21-induced granzyme B-expressing B cells infiltrate tumors and regulate T cells.Semantic proximity Read ↗

IL-17/miR-192/IL-17Rs Regulatory Feedback Loop Facilitates Multiple Myeloma ProgressionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.