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Article

Distinct patterns of bidirectional regulation of mammalian adenylyl cyclases.

The Journal of biological chemistry - 25 Feb 1994

Taussig R, Tang W J, Hepler J R, Gilman A G

Abstract excerpt

The capacities of the alpha subunits of pertussis toxin-sensitive guanine nucleotide-binding regulatory proteins (G proteins) to inhibit different isoforms of mammalian adenylyl cyclases were assessed. Membranes from Sf9 cells infected with recombinant baculoviruses encoding either type I, II, V, or VI adenylyl cyclase were reconstituted with purified G protein subunits. Types V and VI adenylyl cyclase are most...

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PMID: 8119955

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Distinct patterns of bidirectional regulation of mammalian adenylyl cyclases.PMID 8119955Read ↗

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The olfactory G protein G(alphaolf) possesses a lower GDP-affinity and deactivates more rapidly than G(salphashort): consequences for receptor-coupling and adenylyl cyclase activation.Semantic proximity Read ↗

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