Article
Go G-proteins mediate rapid heterologous desensitization of G-protein coupled receptors in Xenopus oocytes.
Journal of cellular physiology - 1 Aug 2005
Van-Ham Irit Itzhaki, Oron Yoram
Abstract excerpt
We have shown previously that responses to lysophosphatidic acid (LPA) in Xenopus oocytes exhibit pronounced rapid homologous desensitization mediated by Go family of G-proteins (Itzhaki-Van Ham et al., 2004, J Cell Physiol, 200: 125-133). The present study was aimed at examining the involvement of Go G-proteins in rapid heterologous desensitization of native and expressed G-protein-coupled receptors in Xenopus...
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