Article
Expression of the Brachyury gene during mesoderm development in differentiating embryonal carcinoma cell cultures
1 Jan 1994
Abstract excerpt
When aggregated and treated with dimethyl sulfoxide (DMSO), P19 embryonal carcinoma cells differentiate into cell types normally derived from the mesoderm and endoderm including epithelium and cardiac and skeletal muscle. The Brachyury gene is expressed transiently in these differentiating cultures several days before the appearance of markers of the differentiated cell types. The expression of Brachyury is not...
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