Article
BMP induction of cardiogenesis in P19 cells requires prior cell-cell interaction(s).
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Aug 2006
Angello John C, Kaestner Stefanie, Welikson Robert E, Buskin Jean N, Hauschka Stephen D
Abstract excerpt
Mouse P19 embryonal carcinoma cells undergo cardiogenesis in response to high density and DMSO. We have derived a clonal subline that undergoes cardiogenesis in response to high density, but without requiring exposure to DMSO. The new subline retains the capacity to differentiate into skeletal muscle and neuronal cells in response to DMSO and retinoic acid. However, upon aggregation, these Oct 4-positive cells,...
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