Repression of SV40 T oncoprotein expression by DMSO.

doi:10.1002/jcp.1041510109

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Article

Repression of SV40 T oncoprotein expression by DMSO.

Journal of cellular physiology - 1 Apr 1992

Witte M M, Parker R F, Wang H, Scott R E

Abstract excerpt

SV40 large T oncoprotein-transformed murine mesenchymal 3T3 T stem cells (CSV3 cells) can be induced to growth arrest and then differentiate into adipocytes. When differentiation occurs, SV40 T oncoprotein expression is repressed (Estervig et al., J Virol 63:2718, 1989). To determine if repression of T oncoprotein expression can also be induced pharmacologically, the effect of a variety of agents that have been...

Topics

Acetamides
Animals
Antigens, Polyomavirus Transforming
Azacitidine
Blotting, Northern
Blotting, Western
Butyrates
Butyric Acid
Cell Line, Transformed
Cell Transformation, Neoplastic
Dimethyl Sulfoxide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Dose-Response Relationship, Drug

Gene Expression Regulation, Neoplastic

Insulin

Interferons

Mice

Phenotype

Stem Cells

Source

Open in PubMed

Identifiers

PMID: 1373148
DOI: 10.1002/jcp.1041510109

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1373148-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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