Article
Induction by adenovirus-5 E1A of the differentiation phenotype of F9 teratocarcinoma cells involves a conserved region (CR1) of E1A.
Biochimica et biophysica acta - 28 Apr 1995
Li H O, Tang X, Kitabayashi I, Gachelin G, Chiu R, Yokoyama K
Abstract excerpt
The effects of the E1A protein of adenovirus-5 on the differentiation program of F9 teratocarcinoma cells were examined by the stable introduction of plasmids that expressed wild-type or mutated forms of E1A. Constitutive expression of plasmids for most of the mutant E1As induced loss of expressi...
Topics
- Adenovirus E1A Proteins
- Amino Acid Sequence
- Cell Differentiation
- Cell Line
- Clone Cells
- Conserved Sequence
- Genes, jun
- Lewis X Antigen
- Mutation
- Plasmids
- Tumor Cells, Cultured