Article
PCR analysis of muscular dystrophy in mdx mice.
Molecular and cell biology of human diseases series - 1 Jan 1993
Chamberlain J S, Phelps S F, Cox G A, Maichele A J, Greenwood A D
Abstract excerpt
PCR amplification has enabled a variety of studies to be performed on the murine dystrophin transcripts. Figure 7.12 displays a summary of the features of the murine dystrophin mRNA that have been described in this article. The location of the mutation in the original mdx mouse is indicated, as are the different spliced forms of the dystrophin transcript. Also shown are the location of various PCR primer binding...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cloning, Molecular
- Dystrophin
- Exons
- Gene Expression
- Genetic Variation
- Mice
- Mice, Mutant Strains
- Molecular Sequence Data