The insulin-like growth factor 1 receptor gene is normally biallelically expressed in human juvenile tissue and tumours.

doi:10.1093/hmg/2.12.2089

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Article

The insulin-like growth factor 1 receptor gene is normally biallelically expressed in human juvenile tissue and tumours.

Human molecular genetics - 1 Dec 1993

Howard T K, Algar E M, Glatz J A, Reeve A E, Smith P J

Abstract excerpt

We have examined insulin-like growth factor 1 receptor (IGF1R) gene expression for evidence of imprinting in 15 informative patients with embryonal tumours. Biallelic expression was observed in all but one sample of normal juvenile kidney and liver, and in 9/10 associated Wilms' tumours, 3/3 hepa...

Topics

Adrenal Gland Neoplasms
Adrenal Glands
Alleles
Animals
Base Sequence
Beckwith-Wiedemann Syndrome
Child
DNA Primers
Female
Gene Expression
Genotype
Hepatoblastoma
Humans
Kidney
Kidney Neoplasms
Liver
Liver Neoplasms
Male

Source

Open in PubMed

Identifiers

PMID: 8111378
DOI: 10.1093/hmg/2.12.2089

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8111378-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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