Article
Mutations of the p53 gene in carcinomas of the urinary system.
Acta pathologica japonica - 1 Dec 1993
Suzuki Y, Tamura G
Abstract excerpt
Deletion of p53, which is an anti-oncogene located on chromosome 17p, was reported to be present at a high incidence in tumor cells of colorectal carcinoma, as well as osteosarcoma of the familial cancer syndrome. Mutations of the p53 gene were investigated in 59 surgical specimens of primary carcinomas of the urinary system from 57 patients, using the polymerase chain reaction single-strand conformation...
Topics
- Aged
- Base Sequence
- Carcinoma, Renal Cell
- Carcinoma, Transitional Cell
- Female
- Genes, p53
- Humans
- Kidney Neoplasms
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
