Article
Charge replacement near the phosphorylatable serine of the myosin regulatory light chain mimics aspects of phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America - 15 Feb 1994
Sweeney H L, Yang Z, Zhi G, Stull J T, Trybus K M
Abstract excerpt
Phosphorylation of the myosin regulatory light chains (RLCs) activates contraction in smooth muscle and modulates force production in striated muscle. RLC phosphorylation changes the net charge in a critical region of the N terminus and thereby may alter interactions between the RLC and myosin he...
Topics
- Amino Acid Sequence
- Animals
- Gizzard, Avian
- Humans
- Models, Biological
- Molecular Sequence Data
- Mollusca
- Movement
- Muscle Contraction
- Muscle, Smooth
- Muscles
- Mutation
- Myosins
- Phosphorylation
- Recombinant Proteins
- Serine
- Structure-Activity Relationship
- Turkeys