Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phosphorylation of the regulatory light chain of myosin in striated muscle: methodological perspectives

15 Apr 2016

Abstract excerpt

Phosphorylation of the regulatory light chain (RLC) of myosin modulates cellular functions such as muscle contraction, mitosis, and cytokinesis. Phosphorylation defects are implicated in a number of diseases. Here we focus on striated muscle where changes in RLC phosphorylation relate to diseases such as hypertrophic cardiomyopathy and muscular dystrophy, or age-related changes. RLC phosphorylation in smooth...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiomyopathy and Myosin Studies
Share to Genetic Neurodegenerative Diseases
Share to Muscle Physiology and Disorders

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27084718
DOI: 10.1007/s00249-016-1128-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phosphorylation of the regulatory light chain of myosin in striated muscle: methodological perspectivesPMID 27084718Read ↗

The role of myosin regulatory light chain phosphorylation in cardiac health and diseaseSemantic proximity Read ↗

Signaling to Myosin Regulatory Light Chain in SarcomeresSemantic proximity Read ↗

The structural and functional effects of myosin regulatory light chain phosphorylation are amplified by increases in sarcomere length and [Ca 2+ ]Semantic proximity Read ↗

Protein phosphorylation and signal transduction in cardiac thin filaments.Semantic proximity Read ↗

Structural and functional responses of mammalian thick filaments to alterations in myosin regulatory light chains.Semantic proximity Read ↗

Myosin regulatory light chain phosphorylation enhances cardiac β-myosin in vitro motility under load.Semantic proximity Read ↗

The effect of myosin RLC phosphorylation in normal and cardiomyopathic mouse hearts.Semantic proximity Read ↗

M-RIP targets myosin phosphatase to stress fibers to regulate myosin light chain phosphorylation in vascular smooth muscle cells.Semantic proximity Read ↗

Mitochondrial Protein Phosphorylation as a Regulatory Modality: Implications for Mitochondrial Dysfunction in Heart FailureSemantic proximity Read ↗

Striated Preferentially Expressed Protein Kinase (SPEG) in Muscle Development, Function, and Disease.Semantic proximity Read ↗

Regulatory light chain mutations associated with cardiomyopathy affect myosin mechanics and kinetics.Semantic proximity Read ↗

Charge replacement near the phosphorylatable serine of the myosin regulatory light chain mimics aspects of phosphorylation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.