Article
Antibodies to glutamic acid decarboxylase in Australian children with insulin-dependent diabetes mellitus and their first-degree relatives.
Pediatric research - 1 Dec 1993
Chen Q Y, Rowley M J, Byrne G C, Jones T W, Tuomi T, Knowles W J, Zimmet P Z, Mackay I R
Abstract excerpt
Antibodies to glutamic acid decarboxylase (GAD), previously known as the 64-kD pancreatic islet cell autoantigen, are an important serologic marker of insulin-dependent diabetes mellitus (IDDM). Antibodies to GAD (anti-GAD) were examined in sera from Australian children with newly diagnosed IDDM...
Topics
- Adolescent
- Adult
- Alleles
- Australia
- Autoantibodies
- Autoantigens
- Child
- Child, Preschool
- Diabetes Mellitus, Type 1
- Female
- Glutamate Decarboxylase
- HLA-DQ Antigens
- HLA-DQ beta-Chains
- Humans
- Islets of Langerhans
- Male
- Middle Aged
- Radioimmunoprecipitation Assay