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Autoantibodies and HLA susceptibility markers in Canadian first-degree relatives of patients with type 1 diabetes.

Annals of the New York Academy of Sciences - 1 Apr 2002

Behme M T, Mahon J L, Dupre J

Abstract excerpt

We examined the frequencies of autoantibodies to glutamate decarboxylase, GAD65, protein tyrosine phosphatase, IA-2/ICA512, and insulin, and of HLA class II markers in ICA-positive first-degree relatives of patients with type 1 diabetes. Our results indicate that while the presence of HLA susceptibility markers is associated with anti-islet autoantibodies, protective DQB1 markers do not absolutely prevent...

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Identifiers

PMID: 12021112
DOI: 10.1111/j.1749-6632.2002.tb02975.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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