Article
Clinical, autoimmune, and HLA characteristics of children diagnosed with type 1 diabetes before 5 years of age.
Pediatrics - 1 Apr 2003
Hathout Eba H, Hartwick Noelle, Fagoaga Omar R, Colacino Anna Rita, Sharkey Jeannine, Racine Michael, Nelsen-Cannarella Sandra, Mace John W
Abstract excerpt
BACKGROUND: Little is known about auxologic, autoimmune, and HLA characteristics specific to children with early-onset diabetes (EOD). HLA subtypes have been shown to play an important part in the determination of islet-cell autoimmunity and in the pace and intensity of the beta-cell destructive process. OBJECTIVES: Our goals were to: 1) outline auxologic, autoimmune, and HLA class II characteristics of children...
Topics
- Autoantibodies
- Autoantigens
- Biomarkers
- Birth Weight
- Body Mass Index
- Child
- Child, Preschool
- Diabetes Mellitus, Type 1
- Genes, MHC Class II
- Genotype
- Glutamate Decarboxylase