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Article

Regulation of chemotaxis by the platelet-derived growth factor receptor-beta.

Nature - 3 Feb 1994

Kundra V, Escobedo J A, Kazlauskas A, Kim H K, Rhee S G, Williams L T, Zetter B R

Abstract excerpt

Chemotaxis is an important component of wound healing, development, immunity and metastasis, yet the signalling pathways that mediate chemotaxis are poorly understood. Platelet-derived growth factor (PDGF) acts both as a mitogen and a chemoattractant. Upon stimulation, the tyrosine kinase PDGF receptor-beta (PDGFR-beta) autophosphorylates and forms a complex that includes SII2(Src homology 2)-domain-containing...

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Identifiers

PMID: 8107807
DOI: 10.1038/367474a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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