Article
Deletion of the E-cadherin gene in hepatitis B virus-positive Chinese hepatocellular carcinomas.
Hepatology (Baltimore, Md.) - 1 Oct 1993
Slagle B L, Zhou Y Z, Birchmeier W, Scorsone K A
Abstract excerpt
Frequent allele loss from chromosome 16q was recently described for human tumors of the breast, prostate gland and liver, indicating the possible presence of a tumor-suppressor gene on that chromosome arm. In this study, the chromosome 16 allele status of 38 hepatocellular carcinomas in Chinese patients was determined with restriction-fragment-length polymorphism analysis. Tumor-specific allele loss was detected...
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