Article
Dopamine D4 receptor variants in unrelated schizophrenic cases and controls.
American journal of medical genetics - 15 Jul 1993
Sommer S S, Lind T J, Heston L L, Sobell J L
Abstract excerpt
The D4 dopamine receptor (D4DR) exists in multiple allelic forms (Van Tol et al.: Nature 358:149-152, 1992) which involve different numbers of a 48 basepair repeat sequence in the putative third cytoplasmic loop. Different binding properties have been reported for at least three of the alleles in...
Topics
- Adult
- Aged
- Alleles
- Binding, Competitive
- Case-Control Studies
- Chi-Square Distribution
- Clozapine
- Electrophoresis, Agar Gel
- Female
- Gene Frequency
- Genetic Variation
- Genotype
- Homozygote
