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Article

Preferential amplification of the paternal allele of the N-myc gene in human neuroblastomas.

Nature genetics - 1 Jun 1993

Cheng J M, Hiemstra J L, Schneider S S, Naumova A, Cheung N K, Cohn S L, Diller L, Sapienza C, Brodeur G M

Abstract excerpt

Genomic imprinting plays a role in influencing the parental origin of genes involved in cancer-specific rearrangements. We have analysed 22 neuroblastomas with N-myc amplification to determine the parental origin of the amplified N-myc allele and the allele that is deleted from chromosome 1p. We analysed DNA from neuroblastoma patients and their parents, using four polymorphisms for 1p and three for the N-myc...

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Source

Identifiers

PMID: 8102299
DOI: 10.1038/ng0693-191

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Preferential amplification of the paternal allele of the N-myc gene in human neuroblastomas.PMID 8102299Read ↗

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