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Allelotype of head and neck paragangliomas: allelic imbalance is confined to the long arm of chromosome 11, the site of the predisposing locus PGL.

Genes, chromosomes & cancer - 1 Oct 1994

Devilee P, van Schothorst E M, Bardoel A F, Bonsing B, Kuipers-Dijkshoorn N, James M R, Fleuren G, van der Mey A G, Cornelisse C J

Abstract excerpt

Paragangliomas of the head and neck region are usually slow growing, benign tumors. A considerable fraction has a positive family history, and the predisposing locus, PGL, has recently been assigned to 11q22-q23. The inheritance pattern of the disease suggests that PGL undergoes maternal genomic imprinting. We have investigated 26 tumor samples from 22 patients with head and neck paragangliomas for the occurrence...

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Identifiers

PMID: 7529551
DOI: 10.1002/gcc.2870110202

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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