Radioresistance induced in rat embryo cells by transfection with the oncogenes H-ras plus v-myc is cell cycle dependent and maximal during S and G2.

doi:10.1080/09553009314450811

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Article

Radioresistance induced in rat embryo cells by transfection with the oncogenes H-ras plus v-myc is cell cycle dependent and maximal during S and G2.

International journal of radiation biology - 1 May 1993

Cheong N, Wang Y, Iliakis G

Abstract excerpt

Rat embryo cells (REC) transformed by the H-ras oncogene plus the cooperating oncogene v-myc are highly resistant to ionizing radiation as compared with the nontransformed parent cells, REC, or immortalized REC. We inquired whether the phenotype of increased radioresistance is maximally expressed...

Topics

Animals
Cell Cycle
Cell Line
Cell Line, Transformed
Genes, ras
Phenotype
Radiation Tolerance
Rats
Transfection

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