Article
Radioresistance induced in rat embryo cells by transfection with the oncogenes H-ras plus v-myc is cell cycle dependent and maximal during S and G2.
International journal of radiation biology - 1 May 1993
Cheong N, Wang Y, Iliakis G
Abstract excerpt
Rat embryo cells (REC) transformed by the H-ras oncogene plus the cooperating oncogene v-myc are highly resistant to ionizing radiation as compared with the nontransformed parent cells, REC, or immortalized REC. We inquired whether the phenotype of increased radioresistance is maximally expressed in certain phases of the cell cycle. We addressed this question by studying the fluctuations in radio-sensitivity...
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