Article
A radioresistant variant derived from a human neuroblastoma cell line is less prone to radiation-induced apoptosis.
Cancer research - 1 Nov 1995
Russell J, Wheldon T E, Stanton P
Abstract excerpt
By subjecting radiosensitive human neuroblastoma IMR 32 cells to a regime of fractionated X-irradiation, a radioresistant variant, XRIMR 32, was obtained. Radiation resistance of XRIMR 32 cells was demonstrated by clonogenic and spheroid regrowth delay assays. The XRIMR 32 cultures were phenotypically unstable, with the resistant phenotype being lost after 3 passages in the absence of radiation-selective...
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