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Article

Sequence analysis of rpoB mutations in rifampin-resistant clinical Mycobacterium tuberculosis isolates from Turkey.

Microbial drug resistance (Larchmont, N.Y.) - 1 Jan 2004

Karahan Zeynep Ceren, Atalay Figen, Uzun Meltem, Erturan Zayre, Atasever Melike, Akar Nejat

Abstract excerpt

Drug-resistant tuberculosis is a serious problem throughout the world. Resistance to Rifampicin (RIF) is mainly caused by the mutations in the rpoB gene coding the beta-subunit of RNA polymerase. In this study, we aimed to detect the distribution of rpoB gene mutations in 80 RIF-resistant clinical Mycobacterium tuberculosis (MTB) isolates from Turkey. The rpoB gene was amplified by PCR and mutations leading to...

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Identifiers

PMID: 15650378
DOI: 10.1089/mdr.2004.10.325

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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