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Detection of Resistance to Isoniazid, Rifampin, and Streptomycin in Clinical Isolates of Mycobacterium tuberculosis by Molecular Methods

1 May 1997

Abstract excerpt

Molecular techniques can detect drug resistance in Mycobacterium tuberculosis, but whether these methods are practical for clinical laboratory use and the management of tuberculosis is unclear. We evaluated several available molecular methods (restriction fragment length polymorphism [RFLP], heteroduplex, and direct DNA sequence analyses) for detecting resistance to isoniazid, rifampin, and streptomycin and...

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PMID: 9142789
DOI: 10.1093/clinids/24.5.894

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Source receipt: pubmed, retrieved 7 Sept 2026.

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