Further evidence of the SA gene as a candidate gene contributing to the hypertension in spontaneously hypertensive rat.

doi:10.1016/0006-291x(92)92350-7

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Article

Further evidence of the SA gene as a candidate gene contributing to the hypertension in spontaneously hypertensive rat.

Biochemical and biophysical research communications - 15 Oct 1992

Iwai N, Kurtz T W, Inagami T

Abstract excerpt

We have recently reported that the allele of the SA gene of the Spontaneously hypertensive rat (SHR) has a capacity to influence blood pressure in a F2 rat population prepared from SHR and Wistar-Kyoto rat. In the present study, we have undertaken a similar genetic co-segregation analysis of the F2 rat population prepared from SHR and Lewis rat. The result indicated that, although overall effects of the SA gene...

Topics

Animals
Base Sequence
Blood Pressure
Blotting, Southern
Brain
Female
Gene Expression
Genotype
Hypertension
Kidney
Male
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oligodeoxyribonucleotides

Polymerase Chain Reaction

RNA, Messenger

Rats

Rats, Inbred Lew

Rats, Inbred SHR

Source

Open in PubMed

Identifiers

PMID: 1417869
DOI: 10.1016/0006-291x(92)92350-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1417869-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Further evidence of the SA gene as a candidate gene contributing to the hypertension in spontaneously hypertensive rat.PMID 1417869Read ↗

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The rat SA gene shows genotype-dependent tissue-specific expression.Semantic proximity Read ↗

Molecular genetics of the SA-gene: cosegregation with hypertension and mapping to rat chromosome 1.Semantic proximity Read ↗

Genetic analysis of the SA and Na+/K+-ATPase alpha1 genes in the Milan hypertensive rat.Semantic proximity Read ↗

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