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Article

Mapping of multiple intestinal neoplasia (Min) to proximal chromosome 18 of the mouse.

Genomics - 1 Jan 1993

Luongo C, Gould K A, Su L K, Kinzler K W, Vogelstein B, Dietrich W, Lander E S, Moser A R

Abstract excerpt

The Min (multiple intestinal neoplasia) mutation of the mouse has been mapped by analyzing the inheritance of restriction fragment length polymorphisms and simple sequence length polymorphisms in progeny from two intraspecific crosses segregating for the Min mutation. Min, a mutant allele of Apc, the mouse homolog of the human APC (adenomatous polyposis coli) gene, maps to proximal chromosome 18. The synteny...

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Source

Identifiers

PMID: 8094372
DOI: 10.1006/geno.1993.1002

Genes

APC
MCC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mapping of multiple intestinal neoplasia (Min) to proximal chromosome 18 of the mouse.PMID 8094372Read ↗

Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene.Semantic proximity Read ↗

Somatic genetic events linked to the Apc locus in intestinal adenomas of the Min mouse.Semantic proximity Read ↗

Multistep carcinogenesis of the colon in Apc(Min/+) mouse.Semantic proximity Read ↗

Identification of Mom7, a novel modifier of Apc(Min/+) on mouse chromosome 18.Semantic proximity Read ↗

Generation of a unique strain of multiple intestinal neoplasia (Apc+/Min‐FCCC) mice with significantly increased numbers of colorectal adenomasSemantic proximity Read ↗

Genetic analysis of intestinal polyp development in Collaborative Cross mice carrying the Apc (Min/+) mutation.Semantic proximity Read ↗

ApcMin, a mutation in the murine Apc gene, predisposes to mammary carcinomas and focal alveolar hyperplasias.Semantic proximity Read ↗

Emergent issues in the genetics of intestinal neoplasia.Semantic proximity Read ↗

The Min (multiple intestinal neoplasia) mutation: its effect on gut epithelial cell differentiation and interaction with a modifier system.Semantic proximity Read ↗

Identification of novel modifier loci of Apc Min affecting mammary tumor development.Semantic proximity Read ↗

Genetic mapping of novel modifiers for ApcMin induced intestinal polyps’ development using the genetic architecture power of the collaborative cross miceSemantic proximity Read ↗

Exclusion of Madh2, Madh4, and Madh7 as candidates for the modifier of Min 2 (Mom2) locus.Semantic proximity Read ↗

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