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A Human Lymphoid Recombinant Cell Line with Functional Human Immunodeficiency Virus Type 1 Envelope

1 Jan 1993

Abstract excerpt

Our goal has been to develop a safe and effective system that would allow us to explore the functions of the human immunodeficiency virus (HIV) envelope. We have generated a human lymphoid cell line (TF228.1.16) that stably expresses functional HIV envelope proteins on its cell surface, and therefore closely mimics the viral envelope and virus-infected cells. The TF228.1.16 line forms syncytia with human cells of...

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PMID: 8094000
DOI: 10.1089/aid.1993.9.23

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