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Article

Nonviral and viral delivery of a human immunodeficiency virus protective gene into primary human T cells.

22 Nov 1994

Abstract excerpt

Because AIDS has been refractory to traditional pharmacologic interventions, alternative approaches have been developed. Although the introduction of specific antiviral genes into T leukemia cells can provide relative resistance to human immunodeficiency virus (HIV) replication, the testing of such genes against primary viral isolates in human CD4+ lymphocytes has been limited, and safety questions remain...

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Identifiers

PMID: 7972106
DOI: 10.1073/pnas.91.24.11581

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Source receipt: pubmed, retrieved 7 Sept 2026.

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