Article
Expanded HIV-1 cellular tropism by phenotypic mixing with murine endogenous retroviruses.
Science (New York, N.Y.) - 16 Feb 1990
Lusso P, di Marzo Veronese F, Ensoli B, Franchini G, Jemma C, DeRocco S E, Kalyanaraman V S, Gallo R C
Abstract excerpt
In view of the current interest in in vivo murine models for acquired immunodeficiency syndrome (AIDS), the interaction between human immunodeficiency virus type 1 (HIV-1) and endogenous murine leukemia virus (MuLV)-related retroviruses was investigated with a human leukemic T cell line (PF-382x)...
Topics
- Acquired Immunodeficiency Syndrome
- Animals
- Antibodies, Monoclonal
- CD4 Antigens
- Cell Line
- Cell Transformation, Viral
- Disease Models, Animal
- HIV-1
- Hematopoietic Stem Cells
- Humans
- Mice
- Phenotype
- Retroviridae
- Viral Proteins
- Virus Replication