Article
Mutation rates in LTR of HTLV-1 in HAM/TSP patients and the carriers are similarly high to Tax/Rex-coding sequence.
Journal of neurovirology - 1 Oct 1996
Saito M, Furukawa Y, Kubota R, Usuku K, Izumo S, Osame M, Yoshida M
Abstract excerpt
The genomic sequence of human T-cell leukemia virus type 1 (HTLV-1) is highly conserved, although minor sequence variations enable classification of the isolates into several subgroups. We previously reported, however, that the Tax-coding sequence of HTLV-1 genome is highly variable in a random fashion within individuals with HAM/TSP and asymptomatic carriers. Here, we describe frequent base substitutions in the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
