Article
Frequent association of p53 gene mutation in invasive bladder cancer.
Cancer research - 15 Mar 1992
Fujimoto K, Yamada Y, Okajima E, Kakizoe T, Sasaki H, Sugimura T, Terada M
Abstract excerpt
Structural alterations of the p53 gene were investigated to elucidate the molecular biological difference between superficial and invasive bladder cancer by polymerase chain reaction single-strand conformation polymorphism analysis. In 25 bladder cancers obtained from 23 patients, p53 gene mutati...
Topics
- Base Sequence
- Carcinoma, Squamous Cell
- Carcinoma, Transitional Cell
- Exons
- Genes, p53
- Humans
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Urinary Bladder Neoplasms
