Article
P53 codon 72 polymorphism in bladder cancer--no evidence of association with increased risk or invasiveness.
Urological research - 1 Dec 2001
Törüner G A, Uçar A, Tez M, Cetinkaya M, Ozen H, Ozçelik T
Abstract excerpt
We studied the effect of the p53 gene Arg72Pro polymorphism on bladder cancer susceptibility in a case control study of 121 bladder cancer patients and 114 age-sex matched controls to determine whether this polymorphism is a biomarker for the risk and how aggressive the disease is. Genomic DNA was obtained from venous blood samples for genotype determination by PCR and restriction digestion. The genotype...
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