p53 expression and mutations in squamous cell carcinoma of the head and neck: expression correlates with the patients' use of tobacco and alcohol.

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Article

p53 expression and mutations in squamous cell carcinoma of the head and neck: expression correlates with the patients' use of tobacco and alcohol.

Cancer detection and prevention - 1 Jan 1994

Field J K, Zoumpourlis V, Spandidos D A, Jones A S

Abstract excerpt

53 expression was assessed in 93 head and neck squamous cell carcinoma patients using CM-1, DO-7, and DO-1 antibodies. Sixty eight percent was found to have positive nuclear staining. The frequency of p53 mutations were investigated in 13 patients using single-stranded conformational polymorphism...

Topics

Alcohol Drinking
Base Sequence
Carcinoma, Squamous Cell
Genes, p53
Head and Neck Neoplasms
Humans
Molecular Sequence Data
Mutation
Smoking
Survival Analysis
Tumor Suppressor Protein p53

Source

Open in PubMed

Identifiers

PMID: 8076382

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8076382-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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