Article
p53 tumor suppressor protein and H-RAS oncogene in maxillofacial tumors: immunohistochemical and genetic investigation, induction chemotherapy response and prognosis evaluation.
Journal of chemotherapy (Florence, Italy) - 1 Oct 1998
Cutilli T, Papola F, Di Emidio P, Corbacelli A
Abstract excerpt
The authors carried out immunohistochemical and genetic research on the tumor suppressor protein p53 and H-RAS oncogene in oromaxillofacial neoplasms. The purpose was to verify, genetically, the presence of correlations between the degree of histopathological overexpression (per cent) of oncogene...
Topics
- Antineoplastic Combined Chemotherapy Protocols
- Carcinoma, Squamous Cell
- Cisplatin
- Combined Modality Therapy
- Facial Neoplasms
- Fluorouracil
- Genes, ras
- Humans
- Immunohistochemistry
- Jaw Neoplasms
- Mutation
- Neoadjuvant Therapy
- Prognosis
- Treatment Outcome
- Tumor Suppressor Protein p53